Opaleye Management Inc.
58 holdingsFiling period: 2026-06-30Current AUM: $947.3Mestimated from latest prices
| # | Ticker | Company | Shares | Reported Value | Current Value | % Portfolio | Change | Date |
|---|---|---|---|---|---|---|---|---|
| 1 | LQDA | Liquidia Corporation | 2.45M | $195.1M | $107.1M | 11.30% | -97,500 | 2026-06-30 |
| 2 | ETON | Eton Pharmaceuticals Inc | 2.86M | $103.5M | $143.5M | 15.15% | -- | 2026-06-30 |
| 3 | HROW | Harrow Inc | 2.40M | $101.9M | $69.5M | 7.33% | -432,230 | 2026-06-30 |
| 4 | IRON | Disc Medicine Inc | 855.0K | $62.5M | $66.4M | 7.01% | +434.0K | 2026-06-30 |
| 5 | — | Urogen Pharma Ltd | 1.44M | $53.0M | $53.0M | 5.59% | +10.0K | 2026-06-30 |
| 6 | APGE | Apogee Therapeutics Inc | 390.0K | $51.8M | $51.8M | 5.46% | -- | 2026-06-30 |
| 7 | — | Meiragtx Hldgs PLC | 3.55M | $48.0M | $48.0M | 5.06% | +1.43M | 2026-06-30 |
| 8 | — | Sol-Gel Technologies Ltd | 500.0K | $37.1M | $37.1M | 3.91% | -- | 2026-06-30 |
| 9 | RZLT | Rezolute Inc | 6.30M | $32.8M | $24.1M | 2.54% | -- | 2026-06-30 |
| 10 | TGTX | TG Therapeutics Inc | 535.0K | $29.4M | $29.3M | 3.09% | -- | 2026-06-30 |
| 11 | IMMX | Immix Biopharma Inc | 2.35M | $24.2M | $18.9M | 2.00% | -- | 2026-06-30 |
| 12 | — | Crescent Biopharma Inc. | 1.32M | $23.7M | $23.7M | 2.51% | +6.7K | 2026-06-30 |
| 13 | STOK | Stoke Therapeutics Inc | 700.0K | $22.9M | $17.8M | 1.88% | -- | 2026-06-30 |
| 14 | ACOG | Alpha Cognition Inc | 2.90M | $20.9M | $24.0M | 2.54% | +333.5K | 2026-06-30 |
| 15 | EWTX | Edgewise Therapeutics Inc | 500.0K | $20.3M | $19.6M | 2.07% | -- | 2026-06-30 |
| 16 | RVMD | Revolution Medicines Inc | 100.0K | $18.7M | $18.4M | 1.94% | -- | 2026-06-30 |
| 17 | GLUE | Monte Rosa Therapeutics Inc | 745.0K | $18.0M | $7.8M | 0.82% | -- | 2026-06-30 |
| 18 | ALMS | Alumis Inc | 550.0K | $15.5M | $3.6M | 0.38% | -- | 2026-06-30 |
| 19 | CDXS | Codexis Inc | 6.79M | $15.3M | $8.8M | 0.93% | -- | 2026-06-30 |
| 20 | REPL | Replimune Group Inc | 1.38M | $15.3M | $17.3M | 1.82% | -- | 2026-06-30 |
| 21 | XOMA | Xoma Royalty Corporation | 338.4K | $14.4M | $14.4M | 1.52% | +38.4K | 2026-06-30 |
| 22 | MBX | Mbx Biosciences Inc | 260.0K | $14.4M | $13.1M | 1.38% | -- | 2026-06-30 |
| 23 | RYTM | Rhythm Pharmaceuticals Inc | 122.5K | $13.6M | $11.0M | 1.16% | -500 | 2026-06-30 |
| 24 | EDIT | Editas Medicine Inc | 3.86M | $12.5M | $9.3M | 0.98% | +1.93M | 2026-06-30 |
| 25 | PTGX | Protagonist Therapeutics Inc | 100.0K | $12.3M | $14.0M | 1.48% | -- | 2026-06-30 |
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