SmartKem, Inc. filed a Certificate of Amendment to its Certificate of Incorporation with the Delaware Secretary of State on August 20, 2026, effectuating a reverse stock split of its common stock on a 1-for-50 basis. The transaction became effective at 5:00 p.m. Eastern Time on that date, converting every fifty shares into one share without altering the par value or authorized share count. Fractional shares were rounded up to the next whole share rather than being paid in cash. Proportionate adjustments were applied to outstanding stock options and warrants, and the number of shares reserved under the equity incentive plan was reduced accordingly. SmartKem operates in the chemical manufacturing industry, specializing in the production of specialty chemicals for various industrial applications.