Siren, L.L.C.
117 holdingsFiling period: 2026-06-30Current AUM: $4.27Bestimated from latest prices
| # | Ticker | Company | Shares | Reported Value | Current Value | % Portfolio | Change | Date |
|---|---|---|---|---|---|---|---|---|
| 1 | SRRK | Scholar Rock Holding Corp | 9.58M | $526.6M | $406.8M | 9.53% | -1,250,000 | 2026-06-30 |
| 2 | KYMR | Kymera Therapeutics Inc | 2.94M | $336.7M | $345.2M | 8.09% | -251,000 | 2026-06-30 |
| 3 | ERAS | Erasca Inc | 11.40M | $208.8M | $173.5M | 4.06% | +153.5K | 2026-06-30 |
| 4 | MANE | Veradermics Inc | 1.66M | $203.5M | $232.9M | 5.46% | +150.0K | 2026-06-30 |
| 5 | TNGX | Tango Therapeutics Inc | 6.18M | $193.2M | $141.4M | 3.31% | +522.3K | 2026-06-30 |
| 6 | RVMD | Revolution Medicines Inc | 900.0K | $168.6M | $167.6M | 3.93% | -210,980 | 2026-06-30 |
| 7 | BCAX | Bicara Therapeutics Inc | 5.60M | $166.4M | $97.9M | 2.29% | -200,000 | 2026-06-30 |
| 8 | ARWR | Arrowhead Pharmaceuticals Inc | 1.72M | $139.8M | $101.3M | 2.37% | +100.0K | 2026-06-30 |
| 9 | ONC | BeOne Medicines AG | 465.0K | $132.5M | $170.2M | 3.99% | -- | 2026-06-30 |
| 10 | EWTX | Edgewise Therapeutics Inc | 3.18M | $129.4M | $125.9M | 2.95% | -1,245,634 | 2026-06-30 |
| 11 | RYTM | Rhythm Pharmaceuticals Inc | 1.14M | $126.2M | $104.7M | 2.45% | +410.8K | 2026-06-30 |
| 12 | LXRX | Lexicon Pharmaceuticals Inc | 44.30M | $106.3M | $65.6M | 1.54% | -- | 2026-06-30 |
| 13 | ELVN | Enliven Therapeutics Inc | 1.77M | $90.1M | $77.5M | 1.82% | +1.03M | 2026-06-30 |
| 14 | SYRE | Spyre Therapeutics Inc | 968.6K | $86.0M | $95.9M | 2.25% | +150.0K | 2026-06-30 |
| 15 | PBLS | Parabilis Medicines Inc | 2.99M | $81.9M | $79.3M | 1.86% | -- | 2026-06-30 |
| 16 | XENE | Xenon Pharmaceuticals Inc | 1.32M | $79.6M | $47.5M | 1.11% | -- | 2026-06-30 |
| 17 | SLDB | Solid Biosciences Inc | 7.69M | $76.8M | $47.6M | 1.12% | -- | 2026-06-30 |
| 18 | ABVX | Abivax SA | 576.0K | $76.8M | $50.1M | 1.17% | -- | 2026-06-30 |
| 19 | COAG | Hemab Therapeutics Holdings Inc | 2.09M | $76.6M | $80.1M | 1.88% | -- | 2026-06-30 |
| 20 | RCUS | Arcus Biosciences Inc | 2.42M | $74.6M | $43.9M | 1.03% | -586,647 | 2026-06-30 |
| 21 | COGT | Cogent Biosciences Inc | 1.86M | $72.0M | $59.5M | 1.39% | +150.0K | 2026-06-30 |
| 22 | RLAY | Relay Therapeutics Inc | 3.65M | $68.3M | $68.8M | 1.61% | -- | 2026-06-30 |
| 23 | TSHA | Taysha Gene Therapies Inc | 9.85M | $67.1M | $41.8M | 0.98% | +1.02M | 2026-06-30 |
| 24 | DFTX | Definium Therapeutics Inc | 1.42M | $66.8M | $52.6M | 1.23% | +500.0K | 2026-06-30 |
| 25 | STOK | Stoke Therapeutics Inc | 2.00M | $65.3M | $52.1M | 1.22% | -- | 2026-06-30 |
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