Spero Therapeutics, Inc. (SPRO)

Pharmaceutical Preparations

Latest Price

$1.07

TTM P/E

7.64

Normalized P/E

TTM Div Yield

Fwd Div Yield

Book Value

0.76

P/B Ratio

1.40

Valuation metrics

EPS: $0.15

Book value / share: $1.05

Formula: √(22.5 × EPS × BVPS)

Graham Number

$1.88

+76% upside

EPS: $0.15

Target P/E: 8×

Formula: EPS × P/E

P/E Fair Value

$1.20

+12% upside

35.6% held by institutions

Institution	Shares	Value	Ownership %	Change	Filing Date
GSK plc	9.19M	$20.0M	15.81%	--	2026-06-30
Pfizer Inc	2.36M	$5.0M	4.06%	--	2026-06-30
Vanguard Capital Management LLC	2.04M	$4.0M	3.50%	+236.3K	2026-06-30
Renaissance Technologies LLC	947.9K	$2.0M	1.63%	-241.3K	2026-06-30
Alphabet Inc.	890.0K	$1.0M	1.53%	--	2026-06-30
BlackRock, Inc.	594.4K	$1.0M	1.02%	+161.2K	2026-06-30
Geode Capital Management, LLC	566.3K	$1.0M	0.97%	+46.4K	2026-06-30
Raymond James Financial Inc	521.7K	$1.0M	0.90%	+518.6K	2026-06-30
Two Sigma Investments, LP	382.8K	--	0.66%	--	2026-06-30
Arrowstreet Capital, Limited Partnership	333.0K	--	0.57%	+182.5K	2026-06-30