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Spero Therapeutics, Inc. (SPRO)

Pharmaceutical Preparations

Latest Price
$1.17
TTM P/E
4.33
Normalized P/E
--
Div Yield
--
Book Value
0.92
P/B Ratio
1.27

Valuation metrics

adjust assumptions →
EPS: $0.15
Book value / share: $1.05
Formula: √(22.5 × EPS × BVPS)
Graham Number
$1.88
+61% upside
EPS: $0.15
Target P/E:
Formula: EPS × P/E
P/E Fair Value
$0.60
49% downside

Institutional Ownership

33.4% held by institutions
InstitutionSharesValueOwnership %ChangeFiling Date
GSK plc9.19M$21.0M15.88%--2026-03-31
Pfizer Inc2.36M$5.0M4.08%--2026-03-31
VANGUARD CAPITAL MANAGEMENT LLC1.80M$4.0M3.11%--2026-03-31
RENAISSANCE TECHNOLOGIES LLC1.19M$2.0M2.05%-90.3K2026-03-31
Alphabet Inc.890.0K$2.0M1.54%--2026-03-31
GEODE CAPITAL MANAGEMENT, LLC519.9K$1.0M0.90%-9.3K2026-03-31
BlackRock, Inc.433.2K$1.0M0.75%-4142026-03-31
CITADEL ADVISORS LLC425.7K--0.74%-45.3K2026-03-31
Anson Funds Management LP422.0K--0.73%-203.1K2026-03-31
GSA CAPITAL PARTNERS LLP278.3K--0.48%+99.4K2026-03-31
View all institutional holders →