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Business Summary
Filings
Ownership
Valuation
Ownership — TSHA
Institutional Holdings
Insider Transactions
US Institutional Ownership
91.3%
Institution
Shares
Value
Ownership %
Change
Filing Date
Avoro Capital Advisors LLC
23.89M
$162.0M
7.34%
+2.19M
2026-06-30
RA CAPITAL MANAGEMENT, L.P.
23.56M
$160.0M
7.24%
--
2026-06-30
GOLDMAN SACHS GROUP INC
22.71M
$154.0M
6.98%
+343.5K
2026-06-30
BlackRock, Inc.
20.69M
$140.0M
6.36%
+2.33M
2026-06-30
Vestal Point Capital, LP
19.41M
$132.0M
5.97%
+1.42M
2026-06-30
MORGAN STANLEY
16.49M
$112.0M
5.07%
-1.48M
2026-06-30
RTW INVESTMENTS, LP
13.56M
$92.0M
4.17%
-120.0K
2026-06-30
FMR LLC
13.34M
$90.0M
4.10%
-984.8K
2026-06-30
VANGUARD CAPITAL MANAGEMENT LLC
12.48M
$84.0M
3.84%
+2.25M
2026-06-30
STATE STREET CORP
11.42M
$77.0M
3.51%
+212.8K
2026-06-30
Siren, L.L.C.
9.85M
$67.0M
3.03%
+1.02M
2026-06-30
Octagon Capital Advisors LP
9.69M
$66.0M
2.98%
+833.3K
2026-06-30
GEODE CAPITAL MANAGEMENT, LLC
6.56M
$44.0M
2.02%
+1.03M
2026-06-30
Polar Capital Holdings Plc
5.12M
$34.0M
1.57%
-537.2K
2026-06-30
MPM BIOIMPACT LLC
4.50M
$30.0M
1.38%
+1.55M
2026-06-30
D. E. Shaw & Co., Inc.
4.40M
$29.0M
1.35%
-28.6K
2026-06-30
BAKER BROS. ADVISORS LP
4.00M
$27.0M
1.23%
--
2026-06-30
WELLINGTON MANAGEMENT GROUP LLP
3.98M
$27.0M
1.22%
+3.35M
2026-06-30
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND
3.89M
$26.0M
1.19%
+1.00M
2026-06-30
Casdin Capital, LLC
3.25M
$22.0M
1.00%
--
2026-06-30
VANGUARD PORTFOLIO MANAGEMENT LLC
3.14M
$21.0M
0.97%
+1.12M
2026-06-30
ADAR1 Capital Management, LLC
3.04M
$20.0M
0.93%
+61.0K
2026-06-30
Pictet Asset Management Holding SA
2.77M
$18.0M
0.85%
+2.75M
2026-06-30
Aberdeen Group plc
2.33M
$15.0M
0.72%
+1.31M
2026-06-30
FARALLON CAPITAL MANAGEMENT, L.L.C.
2.25M
$15.0M
0.69%
--
2026-06-30
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